TUFM


Name

Tu translation elongation factor, mitochondrial

Synonyms

EF-TuMT, EFTU, P43, COXPD4, EFTu [provided by Ensembl, GRCh37]

Location

chr16:28,853,732-28,857,729 (reverse strand)

Summary

This gene encodes a protein which participates in protein translation in mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency resulting in lactic acidosis and fatal encephalopathy. A pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2008]

Ensembl gene ID

ENSG00000178952

Biotype

Protein coding

NCBI gene ID

7284

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Gene Networks

Gene regulatory network (GRN) of the gene in two interaction steps distance for the selected cell types. The network depth can be varied by updating the number in the box of Network Settings. The GRN is based on C3NET algorithm [1]. Each links are the highest association scores for one of the genes of gene pairs. The numbers near the checked boxes refer to the numbers of links contributed by each of the cell types. One can uncheck and remove the links of any of the cell types from the network. The network topology is dynamic and can be re-arranged by pulling a node with a mouse. The solid and dashed lines refer to positive and negative correlations, respectively. Right clicking a node will bring up a menu with additional options. The arrows show the most likely direction of regulation between gene pairs.


[1] [2]





Source Gene Ensembl ID Biotype Corr. Sign Corr. Magnitude (r)