SRM


Name

spermidine synthase

Synonyms

PAPT, SPDSY, SRML1, SPS1 [provided by Ensembl, GRCh37]

Location

chr1:11,114,641-11,120,081 (reverse strand)

Summary

The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor. [provided by RefSeq, Jul 2008]

Ensembl gene ID

ENSG00000116649

Biotype

Protein coding

NCBI gene ID

6723

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Gene Networks

Gene regulatory network (GRN) of the gene in two interaction steps distance for the selected cell types. The network depth can be varied by updating the number in the box of Network Settings. The GRN is based on C3NET algorithm [1]. Each links are the highest association scores for one of the genes of gene pairs. The numbers near the checked boxes refer to the numbers of links contributed by each of the cell types. One can uncheck and remove the links of any of the cell types from the network. The network topology is dynamic and can be re-arranged by pulling a node with a mouse. The solid and dashed lines refer to positive and negative correlations, respectively. Right clicking a node will bring up a menu with additional options. The arrows show the most likely direction of regulation between gene pairs.


[1] [2]





Source Gene Ensembl ID Biotype Corr. Sign Corr. Magnitude (r)