NEU3


Name

sialidase 3 (membrane sialidase)

Synonyms

SIAL3 [provided by Ensembl, GRCh37]

Location

chr11:74,699,179-74,729,938 (forward strand)

Summary

This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer. [provided by RefSeq, Jul 2008]

Ensembl gene ID

ENSG00000162139

Biotype

Protein coding

NCBI gene ID

10825

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Gene Networks

Gene regulatory network (GRN) of the gene in two interaction steps distance for the selected cell types. The network depth can be varied by updating the number in the box of Network Settings. The GRN is based on C3NET algorithm [1]. Each links are the highest association scores for one of the genes of gene pairs. The numbers near the checked boxes refer to the numbers of links contributed by each of the cell types. One can uncheck and remove the links of any of the cell types from the network. The network topology is dynamic and can be re-arranged by pulling a node with a mouse. The solid and dashed lines refer to positive and negative correlations, respectively. Right clicking a node will bring up a menu with additional options. The arrows show the most likely direction of regulation between gene pairs.


[1] [2]





Source Gene Ensembl ID Biotype Corr. Sign Corr. Magnitude (r)