ADCY3


Name

adenylate cyclase 3

Synonyms

AC3, KIAA0511 [provided by Ensembl, GRCh37]

Location

chr2:25,042,038-25,142,708 (reverse strand)

Summary

This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

Ensembl gene ID

ENSG00000138031

Biotype

Protein coding

NCBI gene ID

109

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Gene Networks

Gene regulatory network (GRN) of the gene in two interaction steps distance for the selected cell types. The network depth can be varied by updating the number in the box of Network Settings. The GRN is based on C3NET algorithm [1]. Each links are the highest association scores for one of the genes of gene pairs. The numbers near the checked boxes refer to the numbers of links contributed by each of the cell types. One can uncheck and remove the links of any of the cell types from the network. The network topology is dynamic and can be re-arranged by pulling a node with a mouse. The solid and dashed lines refer to positive and negative correlations, respectively. Right clicking a node will bring up a menu with additional options. The arrows show the most likely direction of regulation between gene pairs.


[1] [2]





Source Gene Ensembl ID Biotype Corr. Sign Corr. Magnitude (r)